Characterizing Cefepime Neurotoxicity: A Systematic Review
نویسندگان
چکیده
منابع مشابه
Characterizing Cefepime Neurotoxicity: A Systematic Review
Neurotoxicity due to cefepime has not been well characterized. We performed a systematic review of the literature and included 5 additional cases from our center. Of the 198 cases found, the mean age was 67 years and 87% of patients had renal dysfunction. The most common clinical features were diminished level of consciousness (80%), disorientation/agitation (47%), and myoclonus (40%). It is wo...
متن کاملCefepime Neurotoxicity in Patients with Renal Insufficiency
Cefepime is a fourth-generation cephalosporin that is active against both gram-positive and gram-negative organisms. It is administered parenterally for the treatment of severe infections. Approximately 85% of the drug is excreted unchanged by the kidneys. Neurotoxicity in patients with renal failure who are treated with cefepime has been reported sporadically. We report on two senile patients ...
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We present here a case of 58-year-old male operated for coronary artery bypass graft surgery with four grafts. He developed neurologic symptoms with injection cefepime which recovered after withdrawal of the drug.
متن کاملCefepime induced neurotoxicity: A case series and review of the literature
Cefepime is a fourth generation cephalosporin which is bactericidal for broad spectrum of organisms. This is a case-series of three patients who presented to our hospital with confusion secondary to cefepime use to treat urinary tract infection (UTI) and health care associated pneumonia (HCAP), after excluding other common etiologies of altered mental status (AMS). Of these three patients, one ...
متن کاملDevelopmental Fluoride Neurotoxicity: A Systematic Review and Meta-Analysis
BACKGROUND Although fluoride may cause neurotoxicity in animal models and acute fluoride poisoning causes neurotoxicity in adults, very little is known of its effects on children's neurodevelopment. OBJECTIVE We performed a systematic review and meta-analysis of published studies to investigate the effects of increased fluoride exposure and delayed neurobehavioral development. METHODS We se...
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ژورنال
عنوان ژورنال: Open Forum Infectious Diseases
سال: 2017
ISSN: 2328-8957
DOI: 10.1093/ofid/ofx170